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9 February 2012A novel multimodal CARS miniaturized microscope
We demonstrate the operation of a novel portable, fibre delivery miniaturized multimodal microscope (exoscope) for
coherent anti-Stokes Raman scattering and two-photon excitation fluorescence imaging using a single Ti:sapphire
femtosecond pulsed laser. This microscope features a large mode area photonic crystal fibre for light delivery, as well as
biaxial scanning microelectromechanical system mirrors and custom miniaturized optics corrected for chromatic
aberration. We demonstrate imaging of polystyrene beads, two photon excitation fluorescence beads in both forward and
backward (epi) directions. This miniaturized exoscope will enable in-vivo imaging of rat spinal cord.