9 February 2012 Studies on wide-field-of-view multiphoton imaging using the flexible clinical multiphoton tomograph MPTflex
Author Affiliations +
Proceedings Volume 8226, Multiphoton Microscopy in the Biomedical Sciences XII; 82262J (2012); doi: 10.1117/12.908733
Event: SPIE BiOS, 2012, San Francisco, California, United States
Abstract
Multiphoton imaging systems are capable of high-resolution 3-D image acquisition of deep tissue. A first commercially available CE-certified biomedical system for subcelluar resolution of human skin has been launched by JenLab company with the DermaInspectR in 2002. The demand for more flexibility caused the development of the MPTflexR, which provides an increased flexibility and accessibility especially for clinical and cosmetic examinations. However the high resolution of clinical multiphoton tomographs are adherent with a small field-of-view (FOV) of about 360×360μm2. Especially time-consuming is the relocation of areas of interest (AOI) like lesions, sweat glands or hair shafts during a multiphoton examination. This limitation can be be overcome by macroscopic large-area (wide-field-ofview) multiphoton tomography, which is tested first within this work.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Martin Weinigel, Hans Georg Breunig, Peter Fischer, Marcel Kellner-Höfer, Rainer Bückle, Karsten König, "Studies on wide-field-of-view multiphoton imaging using the flexible clinical multiphoton tomograph MPTflex", Proc. SPIE 8226, Multiphoton Microscopy in the Biomedical Sciences XII, 82262J (9 February 2012); doi: 10.1117/12.908733; https://doi.org/10.1117/12.908733
PROCEEDINGS
7 PAGES


SHARE
KEYWORDS
Multiphoton tomography

In vitro testing

In vivo imaging

Skin

Tissue optics

Biomedical optics

Harmonic generation

Back to Top