11 February 2012 Modeling the effect of refraction on OCT imaging of lung tissue: a ray-tracing approach
Author Affiliations +
Proceedings Volume 8227, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX; 82271R (2012); doi: 10.1117/12.909649
Event: SPIE BiOS, 2012, San Francisco, California, United States
Abstract
Determining the structure of lung tissue is difficult in ex-vivo samples. Optical coherence tomography (OCT) can image alveoli but ignores optical effects that distort the images. For example, light refracts and changes speed at the alveolar air-tissue surface. We employ ray-tracing to model OCT imaging with directional and speed changes included, using spherical shapes in 2D. Results show apparent thickening of inter-aveolar walls and distortion of shape and depth. Our approach suggests a correction algorithm by combining the model with image analysis. Distortion correction will allow inference of tissue mechanical properties and deeper imaging.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Fatemeh N. Golabchi, Ali Golabchi, Dana H. Brooks, Andrew Gouldstone, Charles A. DiMarzio, "Modeling the effect of refraction on OCT imaging of lung tissue: a ray-tracing approach", Proc. SPIE 8227, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX, 82271R (11 February 2012); doi: 10.1117/12.909649; https://doi.org/10.1117/12.909649
PROCEEDINGS
5 PAGES


SHARE
KEYWORDS
Optical coherence tomography

Tissues

Distortion

Lung

Refraction

Tissue optics

Natural surfaces

Back to Top