2 February 2012 Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging
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Abstract
CARS is meritorious in its ability to perform chemical selective imaging, but its spatial resolution is limited by the diffraction limit of light; however, this limit can be broken by combining CARS and near-field scanning microscope. In this work, we report a novel radially polarized near-field coherent anti-Stokes Raman scattering microscopy (RP-NF-CARS), which uses radially polarized light as excitation to enhance the electric field enhancement under a metallic tip, and improves the signal to background ratio compared with that using linearly polarized excitations. We applied RP-NF-CARS to image nano-scale polystyrene beads and biological system.
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Jian Lin, Kenneth Er, Zhiwei Huang, "Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging", Proc. SPIE 8231, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VIII, 82310B (2 February 2012); doi: 10.1117/12.908476; https://doi.org/10.1117/12.908476
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