6 February 2012 Molecular imaging with surface-enhanced CARS on nanostructures
Author Affiliations +
Proceedings Volume 8234, Plasmonics in Biology and Medicine IX; 82340E (2012) https://doi.org/10.1117/12.908272
Event: SPIE BiOS, 2012, San Francisco, California, United States
Strongly localized electromagnetic fields in the vicinity of nanoparticles and nanogaps greatly enhance spectroscopic signals near them such as in surface-enhanced Raman spectroscopy (SERS). In this work we combine this plasmonic surface enhancement with coherent anti-Stokes Raman spectroscopy (CARS) on reproducible nanostructured surfaces. Surface-enhanced CARS (SECARS) gives rise to very strong enhancements and we find that an enhancement of ~105 can be obtained over standard CARS. Using our nanostructured surfaces, we demonstrate strong correlation between plasmon resonances and surface-enhanced CARS intensities. Furthermore, fast imaging of molecular monolayers is performed. Our work paves the way for reliable single molecule Raman spectroscopy and fast molecular imaging on plasmonic surfaces.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christian Steuwe, Christian Steuwe, Clemens F. Kaminski, Clemens F. Kaminski, Jeremy J. Baumberg, Jeremy J. Baumberg, Sumeet Mahajan, Sumeet Mahajan, "Molecular imaging with surface-enhanced CARS on nanostructures", Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 82340E (6 February 2012); doi: 10.1117/12.908272; https://doi.org/10.1117/12.908272

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