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6 February 2012Surface-enhanced Raman spectroscopy of pterins
Raman spectroscopy is a useful technique in the identification and characterisation of compounds, but in terms of
sensitivity its application is limited. With respect to this the discovery of the surface-enhanced Raman scattering (SERS)
phenomenon has proved monumental, and much research has been carried out over the past 30 years developing the
Pterins are biological compounds that are found in nature in colour pigmentation and in mammalian metabolic pathways.
Moreover, they have been identified in abnormal concentrations in cancer patients, suggesting potential applications in
SERS is an ideal technique to identify these compounds, and both nanoparticle suspensions and pulsed laser deposited
nanoparticle substrates have been used to examine the spectra of xanthopterin, both in aqueous solution and in different