30 January 2012 Alignment and maintenance free all-fiber laser source for CARS microscopy based on frequency conversion by four-wave-mixing
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Abstract
In this contribution we report on a novel approach for pump and stokes pulse generation in extremely compact all-fiber systems using parametric frequency conversion (four-wave-mixing) in photonic-crystal fibers. Representing a completely alignment-free approach, the all-fiber ytterbium-based short-pulse laser system provides intrinsically synchronized tunable two-color picosecond pulses emitted from a single fiber end. The system was designed to address important CH-stretch vibrational resonances. Strong CARS signals are generated and proved by spectroscopic experiments, tuning the laser over the resonance of toluene at 3050cm-1. Furthermore the whole laser setup with a footprint of only 30x30cm2 is mounted on a home-built laser-scanning-microscope and CARS imaging capabilities are verified. The compact turn-key system represents a significant advance for CARS microscopy to enter real-world, in particular bio-medical, applications.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Martin Baumgartl, Martin Baumgartl, Mario Chemnitz, Mario Chemnitz, Cesar Jauregui, Cesar Jauregui, Tobias Meyer, Tobias Meyer, Benjamin Dietzek, Benjamin Dietzek, Jürgen Popp, Jürgen Popp, Jens Limpert, Jens Limpert, Andreas Tünnermann, Andreas Tünnermann, } "Alignment and maintenance free all-fiber laser source for CARS microscopy based on frequency conversion by four-wave-mixing", Proc. SPIE 8247, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XII, 82470F (30 January 2012); doi: 10.1117/12.908170; https://doi.org/10.1117/12.908170
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