8 February 2012 Material processing with 12 femtosecond picojoule laser pulses
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Extremely short near infrared laser pulses (e.g. 10 fs) offer the possibility of precise sub-100nm processing without collateral side effects. Furthermore, the can be employed to excite a variety of absorbers simultaneously due to their broad 100 nm emission band. We demonstrate two-photon fluorescence imaging of green and red fluorescent proteins in living cells as well as two-photon nanolithography with 12 fs laser pulses (750-850 nm) at low microwatt mean power using an 85 MHz laser resonator. At a minimum of 400 μW mean power, direct nanoprocessing in blood cells was realized. Multiphoton ablation in biological specimens follows a P2/τ relation. We were able to create sub-100nm ripples in silicon wafers, to cut glass, gold, and polymers as well as to create transient nanoholes in the membranes of living stem cells and cancer cells for targeted transfection.
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Karsten König, Karsten König, Martin Licht, Martin Licht, Martin Straub, Martin Straub, Aisada Uchugonova, Aisada Uchugonova, } "Material processing with 12 femtosecond picojoule laser pulses", Proc. SPIE 8249, Advanced Fabrication Technologies for Micro/Nano Optics and Photonics V, 82490N (8 February 2012); doi: 10.1117/12.908284; https://doi.org/10.1117/12.908284

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