14 February 2012 Variation analysis of flow rate delivered using a blister pump
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Components for on-chip storage and delivery of liquid reagent are necessary for many commercial applications of lab-on- a-chip technology. One such system uses a 'blister-pack' that is pushed by an actuator. This paper explores the sensitivity of the flow rate produced by a blister-actuator pair to the expected manufacturing variations in its dimensions. A numerical model of the blister-actuator pair is developed and the tool of Variation Simulation Modeling (VSM) is used to determine the robustness of fluid delivery. For a flow-rate requirement of +/- 10%, the number of out-of-spec parts is found to be less than 0.01%. The critical dimensions that need to be controlled to improve robustness are also identified.
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Sivesh Selvakumar, Sivesh Selvakumar, Rodrigo Linares, Rodrigo Linares, Aaron Oppenheimer, Aaron Oppenheimer, Brian Anthony, Brian Anthony, } "Variation analysis of flow rate delivered using a blister pump", Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510I (14 February 2012); doi: 10.1117/12.907502; https://doi.org/10.1117/12.907502

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