3 March 2012 MCNP simulation of absorbed energy and dose by iodinated contrast agent
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The purpose of this study is to investigate the absorbed dose and energy by iodinated contrast medium in diagnostic radiology. A simulation geometry in which an inner sphere (d = 0.2cm, 1cm, 5cm) filled with iodinated contrast medium (or water) is located at the center of a 20cm diameter water sphere was used in simulations performed with MCNP5 codes. Monoenergetic x-rays with energies ranging from 40 to 80keV from a cone beam source were utilized and contrast medium concentration ranged from 100 to 1mg/ml. Absorbed dose ratio (RD) to inner sphere and total absorbed energies ratio (RE) to the whole phantom with and without iodinated contrast medium were investigated. The maximum RD was ~13 for the 0.2cm diameter sphere with 100mg/ml contrast medium. The maximum RE was ~1.05 for the 5cm diameter contrast sphere at 80keV with 100mg/ml contrast medium. Under the same incident photon energy, increasing the inner sphere size from 0.2cm to 5cm caused a ~63% increase in the RD on average. Decreasing the contrast medium concentration from 100 to 10 mg/ml caused a decrease of RD of ~ 76%. A conclusion was reached that although local absorbed dose increase caused by iodinated contrast agent could be high; the increase in total absorbed energy is negligible.
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Wenjun He, Wenjun He, Eugene Mah, Eugene Mah, Walter Huda, Walter Huda, Hai Yao, Hai Yao, } "MCNP simulation of absorbed energy and dose by iodinated contrast agent", Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83131O (3 March 2012); doi: 10.1117/12.911426; https://doi.org/10.1117/12.911426

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