Spectrum optimization of a Talbot-Lau interferometer towards clinical application

Thomas Weber; Florian Bayer; Karl Gödel; Wilhelm Haas; Georg Pelzer; Jens Rieger; André Ritter; Lukas Wucherer; Jürgen Durst; Thilo Michel; Gisela Anton

doi:10.1117/12.911321

3 March 2012 Spectrum optimization of a Talbot-Lau interferometer towards clinical application

Thomas Weber; Florian Bayer; Karl Gödel; Wilhelm Haas; Georg Pelzer; Jens Rieger; André Ritter; Lukas Wucherer; Jürgen Durst; Thilo Michel; Gisela Anton

Author Affiliations +

Proceedings Volume 8313, Medical Imaging 2012: Physics of Medical Imaging; 83135F (2012) https://doi.org/10.1117/12.911321
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

X-ray phase-contrast imaging (XPCI) using a Talbot-Lau interferometer is a promising modality to increase soft-tissue contrast in medical imaging and has drawn the attention of many groups worldwide. Nevertheless, due to the many free parameters to be optimized in a XPCI setup, there's a long way to go to find the optimal geometry, design energy and spectrum for a future clinical application. In this contribution, we present a fast procedure to optimize the visibility response of a Talbot-Lau Interferometer with respect to an introduced filter material. This is done by performing a virtual filtering of the known reference tube spectrum, followed by calculating the visibility using the simulated detector and interferometer responses. Additionally, our procedure can also be used to optimize the general setup lengths, the grating properties or the design energy. We present recent results of the optimization process of our lab setup, where the simulations predict a visibility increase of approximately 72% compared to the non-optimized state. In the future, we are going to extend the functionality of our optimization algorithm to perform simulations that allow the prediction of best suitable spectrum for a given application at a certain noise level tolerated and at the lowest dose possible.

Citation Download Citation

Thomas Weber, Thomas Weber, Florian Bayer, Florian Bayer, Karl Gödel, Karl Gödel, Wilhelm Haas, Wilhelm Haas, Georg Pelzer, Georg Pelzer, Jens Rieger, Jens Rieger, André Ritter, André Ritter, Lukas Wucherer, Lukas Wucherer, Jürgen Durst, Jürgen Durst, Thilo Michel, Thilo Michel, Gisela Anton, Gisela Anton, } "Spectrum optimization of a Talbot-Lau interferometer towards clinical application", Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83135F (3 March 2012); doi: 10.1117/12.911321; https://doi.org/10.1117/12.911321

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $14.40

Non-members: $18.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years