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14 February 2012Computational intelligence techniques for identifying the pectoral muscle region in mammograms
Segmentation of the pectoral muscle is an imperative task in mammographic image analysis. The pectoral edge is
specifically examined by radiologists for abnormal axillary lymph nodes, serves as one of the axes in 3-dimensional
reconstructions, and is one of the fundamental landmarks in mammogram registration and comparison. However, this
region interferes with intensity-based image processing methods and may bias cancer detection algorithms. The purpose
of this study was to develop and evaluate computational intelligence techniques for identifying the pectoral muscle
region in medio-lateral oblique (MLO) view mammograms. After removal of the background region, the mammograms
were segmented using a K-clustered self-organizing map (SOM). Morphological operations were then applied to obtain
an initial estimate of the pectoral muscle region. Shape-based analysis determined which of the K estimates to use in the
final segmentation. The algorithm has been applied to 250 MLO-view Lumisys mammograms from the Digital
Database for Screening Mammography (DDSM). Upon examination, it was discovered that three of the original
mammograms did not contain the pectoral muscle and one contained a clear defect. Of the 246 remaining, 95.94% were
considered to have successfully identified the pectoral muscle region. The results provide a compelling argument for the
effectiveness of computational intelligence techniques for identifying the pectoral muscle region in MLO-view
mammograms.
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H. Erin Rickard, Ruben G. Villao, Adel S. Elmaghraby, "Computational intelligence techniques for identifying the pectoral muscle region in mammograms," Proc. SPIE 8314, Medical Imaging 2012: Image Processing, 831433 (14 February 2012); https://doi.org/10.1117/12.911634