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17 April 2012 Comparison of relative pressures calculated from PC-MRI and SPIV with catheter-based pressure measurements in a stenotic phantom model
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Abstract
This paper describes an experimental system for validation of an approach to non-invasive determination of pressure gradients in stenotic flows as encountered in peripheral arterial disease. Pressure gradient across a Gaussian-shaped 87% area stenosis phantom was estimated by solving the pressure Poisson equation (PPE) for a steady flow mimicking the blood flow through the human iliac artery. The velocity field needed to solve the pressure equation was obtained using Phase-Contrast MRI (PC-MRI) and Stereoscopic Particle Image Velocimetry (SPIV). Steady flow rate of 46.9 ml/s was used, which corresponds to a Reynolds number of 188 and 595 at the inlet and stenosis throat, respectively (in the range of mean Reynolds number encountered, in-vivo). Results of PC-MRI and SPIV have been compared to the pressures measured directly by a pressure catheter transducer. The reconstructed pressure drop along the centerline overestimates the catheter reference pressure drop by 8.5% and 10.5% for PC_MRI and SPIV methods, respectively.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Iman Khodarahmi, Mostafa Shakeri, Melanie Kotys-Traughber, Michael K. Sharp, and Amir A. Amini "Comparison of relative pressures calculated from PC-MRI and SPIV with catheter-based pressure measurements in a stenotic phantom model", Proc. SPIE 8317, Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging, 83170E (17 April 2012); https://doi.org/10.1117/12.914716
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