Managing and querying whole slide images

Fusheng Wang; Tae W. Oh; Cristobal Vergara-Niedermayr; Tahsin Kurc; Joel Saltz

doi:10.1117/12.912388

16 February 2012 Managing and querying whole slide images

Fusheng Wang, Tae W. Oh, Cristobal Vergara-Niedermayr, Tahsin Kurc, Joel Saltz

Proceedings Volume 8319, Medical Imaging 2012: Advanced PACS-based Imaging Informatics and Therapeutic Applications; 83190J (2012) https://doi.org/10.1117/12.912388
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

High-resolution pathology images provide rich information about the morphological and functional characteristics of biological systems, and are transforming the field of pathology into a new era. To facilitate the use of digital pathology imaging for biomedical research and clinical diagnosis, it is essential to manage and query both whole slide images (WSI) and analytical results generated from images, such as annotations made by humans and computed features and classifications made by computer algorithms. There are unique requirements on modeling, managing and querying whole slide images, including compatibility with standards, scalability, support of image queries at multiple granularities, and support of integrated queries between images and derived results from the images. In this paper, we present our work on developing the Pathology Image Database System (PIDB), which is a standard oriented image database to support retrieval of images, tiles, regions and analytical results, image visualization and experiment management through a unified interface and architecture. The system is deployed for managing and querying whole slide images for In Silico brain tumor studies at Emory University. PIDB is generic and open source, and can be easily used to support other biomedical research projects. It has the potential to be integrated into a Picture Archiving and Communications System (PACS) with powerful query capabilities to support pathology imaging.

Citation Download Citation

Fusheng Wang, Tae W. Oh, Cristobal Vergara-Niedermayr, Tahsin Kurc, and Joel Saltz "Managing and querying whole slide images", Proc. SPIE 8319, Medical Imaging 2012: Advanced PACS-based Imaging Informatics and Therapeutic Applications, 83190J (16 February 2012); https://doi.org/10.1117/12.912388

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available