24 February 2012 Detection of breast microcalcifications using synthetic-aperture ultrasound
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Ultrasound could be an attractive imaging modality for detecting breast microcalcifications, but it requires significant improvement in image resolution and quality. Recently, we have used tissue-equivalent phantoms to demonstrate that synthetic-aperture ultrasound has the potential to detect small targets. In this paper, we study the in vivo imaging capability of a real-time synthetic-aperture ultrasound system for detecting breast microcalcifications. This LANL's (Los Alamos National Laboratory's) custom built synthetic-aperture ultrasound system has a maximum frame rate of 25 Hz, and is one of the very first medical devices capable of acquiring synthetic-aperture ultrasound data and forming ultrasound images in real time, making the synthetic-aperture ultrasound feasible for clinical applications. We recruit patients whose screening mammograms show breast microcalcifications, and use LANL's synthetic-aperture ultrasound system to scan the regions with microcalcifications. Our preliminary in vivo patient imaging results demonstrate that synthetic-aperture ultrasound is a promising imaging modality for detecting breast microcalcifications.
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Lianjie Huang, Lianjie Huang, Yassin Labyed, Yassin Labyed, Youzuo Lin, Youzuo Lin, Zhigang Zhang, Zhigang Zhang, Jennifer Pohl, Jennifer Pohl, Daniel Sandoval, Daniel Sandoval, Michael Williamson, Michael Williamson, "Detection of breast microcalcifications using synthetic-aperture ultrasound", Proc. SPIE 8320, Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy, 83200H (24 February 2012); doi: 10.1117/12.910656; https://doi.org/10.1117/12.910656

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