13 March 2012 Three-dimensional full-range complex Fourier domain optical coherence tomography for in-vivo volumetric imaging of human skin
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Abstract
A three dimensional full-range complex Fourier domain optical coherence tomography (complex FDOCT) system based on sinusoidal phase-modulating method is proposed. With the system, the range of imaging depth is doubled and the sensitivity degradation with the lateral scan distance is avoided. Fourier analysis of B-scan data along lateral scan distance is used for reconstructing the complex spectral interferograms. The B-scan based Fourier method improves the system tolerance of sample movement and makes data processing less time consuming. In vivo volumetric imaging of human skin with the proposed full-range FDOCT system is demonstrated. The mirror image rejection ratio is about 30 dB. The stratum corneum, the epidermis and the upper dermis of skin can be clearly identified in the reconstructed three dimensional FDOCT images.
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Nan Nan, Nan Nan, Peng Bu, Peng Bu, Xin Guo, Xin Guo, Xiangzhao Wang, Xiangzhao Wang, "Three-dimensional full-range complex Fourier domain optical coherence tomography for in-vivo volumetric imaging of human skin", Proc. SPIE 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011), 83290O (13 March 2012); doi: 10.1117/12.919095; https://doi.org/10.1117/12.919095
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