13 March 2012 Liver cancer diagnosis by fluorescence spectra of blood and urine
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Liver cancer or hepatocellular carcinoma (HCC) is a serious malady with only 10% survival rate. HCC incidence and mortality both are highest in China. This disease is detected and diagnosed by ultra sound, CT or MRI scans which are quite expensive. Also the discrimination between cirrhosis and HCC are poor by this imaging technique. The conventional tissue biopsy is quite invasive and painful. In this context, in the new diagnostic procedure presented in this paper, all the three liver malfunctions, particularly liver cancer, could be detected and discriminated by the spectral feature of blood and urine with accuracy about 80%. All that we need are 5 ml of blood and 5 ml of urine. Hence this inexpensive non invasive, optical technique will have significant impact in screening, diagnosis and also prognosis of HCC in large segment of people in the populous Asian countries.
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Mohamad Saleh AlSalhi, Mohamad Saleh AlSalhi, Abdulaziz Mayuof Al Mehmadi, Abdulaziz Mayuof Al Mehmadi, Aiman Abdoo, Aiman Abdoo, Vadivel Masilamani, Vadivel Masilamani, } "Liver cancer diagnosis by fluorescence spectra of blood and urine", Proc. SPIE 8329, Tenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011), 83290X (13 March 2012); doi: 10.1117/12.923788; https://doi.org/10.1117/12.923788

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