8 June 2012 Shape-based nuclei area of digitized pap smear images
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Proceedings Volume 8334, Fourth International Conference on Digital Image Processing (ICDIP 2012); 83344J (2012) https://doi.org/10.1117/12.975658
Event: Fourth International Conference on Digital Image Processing (ICDIP 2012), 2012, Kuala Lumpur, Malaysia
Abstract
Nuclei of the epithelial of Pap smear cells are important risk indicator of cervical cancers. Pathologist uses the changing of the area of the nuclei to determine whether cells are normal or abnormal. It means that having correct measurement of the area of nuclei is important on the pap smears assessment. Our paper present a novel approach to analyze the shape of nuclei in pap smear images and measuring the area of nuclei. We conducted a study to measure the area of nuclei automatically by calculating the number of pixels contained in each of the segmented nuclei. For comparison, we performed measurements of nuclei area using the ellipse area approximation. The result of the t-test confirmed that there were similarity between elliptical area approximation and automatic segmented nuclei-area at 0.5% level of significance.
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Izzati Muhimmah, Izzati Muhimmah, Rahadian Kurniawan, Rahadian Kurniawan, } "Shape-based nuclei area of digitized pap smear images", Proc. SPIE 8334, Fourth International Conference on Digital Image Processing (ICDIP 2012), 83344J (8 June 2012); doi: 10.1117/12.975658; https://doi.org/10.1117/12.975658
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