Magnetic Resonance Imaging (MRI) is a medical imaging technique used in radiology to visualize the detailed internal
structure and body soft tissues in complete 3D image. MRI performs best when optimal imaging parameters such as
contrast, signal to noise ratio (SNR), spatial resolution and total scan time are utilized. However, due to a variety of
imaging parameters that differ with the manufacturer, a calibration medium that allows the control of these parameters is
necessary. Therefore, a phantom that behaves similar to human soft tissue is developed to replace a real human. Polymer
gel is novel material that has great potential in the medical imaging. Since very few have focused on examining the
behavior of polymer lesions, the motivation of this study is to develop a polymer gel phantom, especially for liver, with
embedded lesions. Both the phantom and lesions should be capable of reflecting T1 and T2 relaxation values through
various characterization processes.
In this paper, phantom and lesion particles were fabricated with carrageenan as a gelling agent by physical aggregation.
Agar was used as supplementary gelling agent and T2 modifier and Gd-DTPA as T1 modifier. The polymer gel samples
were fabricated by varying the concentrations of the gelling agent, and T1 and T2 modifiers. The lesion particles were
obtained by extracting molten polymer gel solution in chilled oil bath to obtain spherical shape. The polymer gel
properties including density, elastic modulus, dielectric constant and optical properties were measured to compare with
human tissue values for long period of time.