7 November 2012 Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer
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Proceedings Volume 8421, OFS2012 22nd International Conference on Optical Fiber Sensors; 84215Q (2012) https://doi.org/10.1117/12.974989
Event: OFS2012 22nd International Conference on Optical Fiber Sensor, 2012, Beijing, China
Abstract
The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ~3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).
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Guiying Ma, Guiying Ma, A. Ping Zhang, A. Ping Zhang, Guofeng Yan, Guofeng Yan, Yinbing Bai, Yinbing Bai, Yichuan Hu, Yichuan Hu, Xuesong Ye, Xuesong Ye, } "Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer", Proc. SPIE 8421, OFS2012 22nd International Conference on Optical Fiber Sensors, 84215Q (7 November 2012); doi: 10.1117/12.974989; https://doi.org/10.1117/12.974989
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