1 May 2012 Fabrication of ZnO nanostructures and their application in biomedicine
Author Affiliations +
Proceedings Volume 8424, Nanophotonics IV; 84242Q (2012); doi: 10.1117/12.922406
Event: SPIE Photonics Europe, 2012, Brussels, Belgium
Abstract
In this study, we synthesized different types of ZnO samples (thin and nanostructured films) and investigated their potential application in biomedicine. The properties of ZnO films are strongly dependent on the synthesis process and the experimental conditions. Thus, the samples were prepared by pulsed laser deposition (PLD), which allows excellent control over the stoichiometry and surface morphology. Cell suspensions of the same concentration and volume (i.e. same number of cells) were seeded on each sample. The subjects of interest were 3T3 fibroblast, MCF-7 and HeLa cancer cells. The influence of the ZnO surface morphology on the viability of these three different cell cultures was studied. The cell type defines the appropriate surface morphology for cell culturing. The nanoscale morphology of the samples supports the HeLa cell viability, while only a small quantity of MCF-7 cells are able to adhere, spread and survive on them.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. Og. Dikovska, N. Ts. Tsankov, R. Toshkova, E. Gardeva, L. Yossifova, N. N. Nedyalkov, P. A. Atanasov, "Fabrication of ZnO nanostructures and their application in biomedicine", Proc. SPIE 8424, Nanophotonics IV, 84242Q (1 May 2012); doi: 10.1117/12.922406; https://doi.org/10.1117/12.922406
PROCEEDINGS
7 PAGES


SHARE
KEYWORDS
Zinc oxide

Tumors

Oxygen

Nanostructuring

Atomic force microscopy

Photomicroscopy

Nanostructures

Back to Top