8 May 2012 Optical trapping detects colored noise in the fluctuations of an extended DNA molecule
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Proceedings Volume 8427, Biophotonics: Photonic Solutions for Better Health Care III; 84270V (2012); doi: 10.1117/12.921354
Event: SPIE Photonics Europe, 2012, Brussels, Belgium
Abstract
We studied fluctuations of an optically trapped bead connected to a single DNA molecule anchored between the bead and a cover glass or between two optically trapped beads. Power spectral densities of the bead position for different extensions of the molecule were compared with the power spectral density of the position fluctuations of the same bead without the molecule attached. Experiments showed that the fluctuations of the DNA molecule extended up to 80% by a force of 3 pN include the colored noise contribution with spectral dependence 1/fα with α~ 0.75.
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Ignacio A. Martínez, Saurabh Raj, Dmitri Petrov, "Optical trapping detects colored noise in the fluctuations of an extended DNA molecule", Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 84270V (8 May 2012); doi: 10.1117/12.921354; https://doi.org/10.1117/12.921354
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KEYWORDS
Molecules

Optical tweezers

Polymers

Sensors

Calibration

Optical calibration

Signal to noise ratio

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