9 May 2012 Waveguide-type localized plasmon resonance biosensor for noninvasive glucose concentration detection
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Abstract
The waveguide type biosensors for noninvasive glucose detection based on LSPR of silver nanoparticles were fabricated by thermal diffusion in UV-irradiated photo-thermo-refractive (PTR) glasses and by ion-exchange method in sodiumborosilicate glasses in water vapor atmosphere. The optical and structural properties of the obtained nanocomposites were investigated. The D-glucose/D-galactose binding protein (GGBP) was chosen as a sensitive element of biosensor and successable immobilized on top of PTR glass. The change in absorption spectra were judged due to the presence of GGBP on the substrate surface.
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A. V. Nashchekin, V. N. Nevedomskiy, P. A. Obraztsov, O. V. Stepanenko, A. I. Sidorov, O. A. Usov, K. K. Turoverov, S. G. Konnikov, "Waveguide-type localized plasmon resonance biosensor for noninvasive glucose concentration detection", Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 842739 (9 May 2012); doi: 10.1117/12.922454; https://doi.org/10.1117/12.922454
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