8 May 2012 Porosity at photo-induced fat cell lipolysis
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Abstract
The "specific structures" on the fat cells' membranes in vitro as a result of photodynamic treatment was registered. These structures were identified as cytoplasm/oil microdrops flowed out through the pores in the membranes. The impact of Brilliant Green dissolved in water-ethanol solutions and irradiation by a LED lamp on the quantity and size of "specific structures" on the membranes was investigated. It was demonstrated that optical selective action on fat cells sensitized by Brilliant Green led to the growth of "specific structures" (pores) number during the time interval after light exposure. A high degree of correlation between the optical clearing of fat tissue and quantity of "specific structures" (pores) was found. This result proves our early prediction about mechanism of light-induced fat cells' lipolysis via increased cell membrane porosity.
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V. A. Doubrovsky, V. A. Doubrovsky, I. Yu. Yanina, I. Yu. Yanina, V. V. Tuchin, V. V. Tuchin, } "Porosity at photo-induced fat cell lipolysis", Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 842748 (8 May 2012); doi: 10.1117/12.924117; https://doi.org/10.1117/12.924117
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