11 May 2012 Real-time and low-cost biosensors based on photonic bandgap structures
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We discuss the development of label-free, real-time and low-cost biosensors based on planar photonic bandgap (PBG) structures. We propose a novel power-based readout technique where the PBG shift is indirectly tracked by simply exciting the photonic sensing structure with a filtered broadband source and measuring the output power with a power meter. Therefore, the use of either tunable lasers or spectrum analyzers to continuously acquire the transmission spectrum of the structure, as done for other spectrum-based sensing techniques, is avoided. We have used this technique both for the sensing of refractive index variations as well as for the label-free detection of antibodies, showing high sensitivities and low detection limits, which demonstrate its high potential for the development of label-free, real-time and low-cost photonic biosensors. Furthermore, the use of broadband sources and detectors for the readout of the photonic sensors will also allow their integration, thus achieving a completely electrically accessed photonic biosensing device.
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J. García-Rupérez, J. G. Castelló, V. Toccafondo, P. Pérez-Millán, "Real-time and low-cost biosensors based on photonic bandgap structures", Proc. SPIE 8431, Silicon Photonics and Photonic Integrated Circuits III, 84310O (11 May 2012); doi: 10.1117/12.921934; https://doi.org/10.1117/12.921934

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