9 May 2012 200 ps FWHM and 100 MHz repetition rate ultrafast gated camera for optical medical functional imaging
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Abstract
The paper describes the realization of a complete optical imaging device to clinical applications like brain functional imaging by time-resolved, spectroscopic diffuse optical tomography. The entire instrument is assembled in a unique setup that includes a light source, an ultrafast time-gated intensified camera and all the electronic control units. The light source is composed of four near infrared laser diodes driven by a nanosecond electrical pulse generator working in a sequential mode at a repetition rate of 100 MHz. The resulting light pulses, at four wavelengths, are less than 80 ps FWHM. They are injected in a four-furcated optical fiber ended with a frontal light distributor to obtain a uniform illumination spot directed towards the head of the patient. Photons back-scattered by the subject are detected by the intensified CCD camera; there are resolved according to their time of flight inside the head. The very core of the intensified camera system is the image intensifier tube and its associated electrical pulse generator. The ultrafast generator produces 50 V pulses, at a repetition rate of 100 MHz and a width corresponding to the 200 ps requested gate. The photocathode and the Micro-Channel-Plate of the intensifier have been specially designed to enhance the electromagnetic wave propagation and reduce the power loss and heat that are prejudicial to the quality of the image. The whole instrumentation system is controlled by an FPGA based module. The timing of the light pulses and the photocathode gating is precisely adjustable with a step of 9 ps. All the acquisition parameters are configurable via software through an USB plug and the image data are transferred to a PC via an Ethernet link. The compactness of the device makes it a perfect device for bedside clinical applications.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Wilfried Uhring, Wilfried Uhring, Patrick Poulet, Patrick Poulet, Walter Hanselmann, Walter Hanselmann, René Glazenborg, René Glazenborg, Virginie Zint, Virginie Zint, Farouk Nouizi, Farouk Nouizi, Benoit Dubois, Benoit Dubois, Werner Hirschi, Werner Hirschi, } "200 ps FWHM and 100 MHz repetition rate ultrafast gated camera for optical medical functional imaging", Proc. SPIE 8439, Optical Sensing and Detection II, 84392L (9 May 2012); doi: 10.1117/12.922123; https://doi.org/10.1117/12.922123
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