AISA hyperspectral imagers have been utilized in airborne applications for various defense related Intelligence, Surveillance and Reconnaissance (ISR) applications. In expanding the utility and capabilities of hyperspectral imagers for defense related applications, the implementation in a ground scanning configuration for check-point and forensic purposes has been achieved. System specifications, design, and operational considerations for a fully automated, near real-time target detection capability are presented. The system utilizes modularized software architecture, combining C++ command, capture, calibration, and messaging functions with drop-in IDL exploitation module for detection algorithm and target set flexibility. Performance capability against known defense related targets of interest have been tested, verified, and are presented utilizing full 400-2450nm spectral range provided by combined AisaEAGLE and AisaHAWK hyperspectral imagers. Initial results are also described for a new extended InGaAs system, covering 585-1630nm to provide a similar capability for integrations which have size, weight, and power restrictions.