Resting state brain networks and their  implications in neurodegenerative disease

William Seunghyun Sohn; Kwangsun Yoo; Jinho Kim; Yong Jeong

doi:10.1117/12.2000254

24 October 2012 Resting state brain networks and their implications in neurodegenerative disease

William Seunghyun Sohn, Kwangsun Yoo, Jinho Kim, Yong Jeong

Proceedings Volume 8548, Nanosystems in Engineering and Medicine; 85483Z (2012) https://doi.org/10.1117/12.2000254
Event: SPIE Nanosystems in Engineering + Medicine, 2012, Incheon, Korea, Republic of

Abstract

Neurons are the basic units of the brain, and form network by connecting via synapses. So far, there have been limited ways to measure the brain networks. Recently, various imaging modalities are widely used for this purpose. In this paper, brain network mapping using resting state fMRI will be introduced with several applications including neurodegenerative disease such as Alzheimer’s disease, frontotemporal lobar degeneration and Parkinson’s disease. The resting functional connectivity using intrinsic functional connectivity in mouse is useful since we can take advantage of perturbation or stimulation of certain nodes of the network. The study of brain connectivity will open a new era in understanding of brain and diseases thus will be an essential foundation for future research.

Citation Download Citation

William Seunghyun Sohn, Kwangsun Yoo, Jinho Kim, and Yong Jeong "Resting state brain networks and their implications in neurodegenerative disease", Proc. SPIE 8548, Nanosystems in Engineering and Medicine, 85483Z (24 October 2012); https://doi.org/10.1117/12.2000254

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