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11 December 2012 Indirect photobiomodulation in functional networks
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Photobiomodulation (PBM) is a non-damaged modulation of laser irradiation or monochromatic light (LI) on a biosystem function. It depends on whether the function is in its function-specific homeostasis (FSH), a negative feedback response for the function to be performed perfectly. Many redundant pathways (RPs) maintain the same cellular function. The full activation of any of RPs can maintain a normal function in its FSH, but partial activation of all the RPs can only maintain a dysfunctional function far from its FSH. A PBM may self-adaptively modulate the activation of a partially activated RP of a normal function until it is fully activated and the normal function is then upgraded. This PBM is called indirect PBM (iPBM). The iPBM on cells such as tumor cells, myoblast cells and fibroblasts and other biosystems and their applications would be reviewed in this paper.
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Timon Cheng-Yi Liu, Wei-Wei Zhu, and Xiang-Bo Yang "Indirect photobiomodulation in functional networks", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85530D (11 December 2012);

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