11 December 2012 Phantom testing of a novel endoscopic OCT probe: a prelude to clinical in-vivo laryngeal use
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Abstract
Optical coherence tomography is a novel imaging technique providing potentially high resolution tri-dimensional images of tissue microstructure up to 2-3mm deep. We present pre-clinical data from a novel miniaturised OCT probe utilised for endoscopic imaging of laryngeal mucosa. A 1300nm SS-OCT probe was passed in tandem with a flexible fibreoptic nasoendoscope into the larynx of a manikin. Ex vivo OCT images were acquired using a desktop 1300nm TD-OCT imaging system. The feasibility, robustness and safety of this set-up was demonstrated as a preliminary step to extending the use of this assembly to a clinical patient cohort with varying laryngeal pathologies.
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Taran Tatla, J. Y. Pang, R. Cernat, G. Dobre, P. J. Tadrous, A. Bradu, G. Gelikonov, V. Gelikonov, A. Gh. Podoleanu, "Phantom testing of a novel endoscopic OCT probe: a prelude to clinical in-vivo laryngeal use", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85530S (11 December 2012); doi: 10.1117/12.981713; https://doi.org/10.1117/12.981713
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