Fast reconstruction of Raman spectra from narrow-band measurements based on Wiener estimation

Shuo Chen; Yi Hong Ong; Quan Liu

doi:10.1117/12.999473

11 December 2012 Fast reconstruction of Raman spectra from narrow-band measurements based on Wiener estimation

Shuo Chen, Yi Hong Ong, Quan Liu

Proceedings Volume 8553, Optics in Health Care and Biomedical Optics V; 85531R (2012) https://doi.org/10.1117/12.999473
Event: Photonics Asia, 2012, Beijing, China

Abstract

Raman spectroscopy has demonstrated great potential in the study of biological molecules in a variety of biomedical applications. But slow data acquisition due to weak Raman signals from these molecules has prevented its wide use especially in an imaging setup. We propose a novel method to reconstruct the entire Raman spectrum from a few narrow-band measurements based on Wiener estimation. This method has been tested on Raman spectra from individual cells and shown fast speed and excellent accuracy. This method represents a new direction to speed up Raman data acquisition in an imaging setup to investigate fast changing phenomena.

Citation Download Citation

Shuo Chen, Yi Hong Ong, and Quan Liu "Fast reconstruction of Raman spectra from narrow-band measurements based on Wiener estimation", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85531R (11 December 2012); https://doi.org/10.1117/12.999473

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