8 March 2013 Flexible optitrode for localized light delivery and electrical recording
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Abstract
We present two innovative design concepts of integrated flexible neural probe for deep brain optical stimulation and electrical recording, termed as “optitrode”. In the first one, a hybrid annular light pipe is built around a tetrode by V-groove guided capillary assembly (VGCA), by which a single or multiple microwires can be packaged inside the light pipe with high precision. In the second design, thin-film microelectrodes and wires are patterned on an optical fiber by proximity ion beam lithography. These designs address a major limitation on the length-to-diameter ratio, achieving > 500 (>5 cm long, <100 μm diameter). The highly flexible nature of optitrode could be critical for minimally-invasive implantation as well as long-term operation.
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Szu-Te Lin, Szu-Te Lin, Mufaddal Gheewala, Mufaddal Gheewala, John A. Dani, John A. Dani, John C. Wolfe, John C. Wolfe, Wei-Chuan Shih, Wei-Chuan Shih, } "Flexible optitrode for localized light delivery and electrical recording", Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 85655Y (8 March 2013); doi: 10.1117/12.2005707; https://doi.org/10.1117/12.2005707
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