25 March 2013 Multimodal optical device for early childhood caries: a clinical prototype
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Proceedings Volume 8566, Lasers in Dentistry XIX; 856603 (2013) https://doi.org/10.1117/12.2006240
Event: SPIE BiOS, 2013, San Francisco, California, United States
Abstract
There is currently a need for a safe and effective way to detect and diagnose early childhood caries. We have developed a multimodal optical clinical prototype for testing in vivo. The device can be used to quickly image and screen for any signs of demineralized enamel by obtaining high-resolution and highcontrast surface images using a 405-nm laser as the illumination source, as well as obtaining autofluorescence and bacterial fluorescence images. Then, when a suspicious region is located, the device can perform dual laser fluorescence spectroscopy using 405-nm and 532-nm laser excitation which is used to compute an autofluorescence ratio. This ratio can be used to quantitatively diagnose enamel health. The device is tested on four in vivo test subjects as well as 17 extracted teeth with clinically diagnosed carious lesions. The device was able to provide detailed images which served to screen for suspected early caries. The autofluorescence ratios obtained from the extracted teeth were able to discriminate between healthy and unhealthy enamel. Therefore, the clinical prototype demonstrates feasibility in screening for and in quantitatively diagnosing healthy from demineralized enamel.
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Liang Zhang, Liang Zhang, Jeremy S. Ridge, Jeremy S. Ridge, Leonard Y. Nelson, Leonard Y. Nelson, Joel H. Berg, Joel H. Berg, Eric J. Seibel, Eric J. Seibel, } "Multimodal optical device for early childhood caries: a clinical prototype", Proc. SPIE 8566, Lasers in Dentistry XIX, 856603 (25 March 2013); doi: 10.1117/12.2006240; https://doi.org/10.1117/12.2006240
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