LEDs as excitation source for time resolved singlet oxygen
luminescence detection in cell suspensions

Steffen Hackbarth; Annegret Preuss; Tobias Perna; Jan Schlothauer; Beate Röder

doi:10.1117/12.2008185

13 March 2013 LEDs as excitation source for time resolved singlet oxygen luminescence detection in cell suspensions

Steffen Hackbarth, Annegret Preuss, Tobias Perna, Jan Schlothauer, Beate Röder

Proceedings Volume 8568, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXII; 85680W (2013) https://doi.org/10.1117/12.2008185
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

LEDs have more and more influence on daily life as well as on scientific equipment. In this paper we want to report results gained with the first LED powered setup for time resolved detection of the singlet oxygen luminescence in solution as well as in cell suspension. The results show, that this setup can compete with the best laser powered setups worldwide. The high sensitivity comes along with a superior long term stability and wavelength versatility. Setups based on LED excitation can simplify the technical part of such measurement very much and reduce the costs, making this technology available for a wider scientific community.

Citation Download Citation

Steffen Hackbarth, Annegret Preuss, Tobias Perna, Jan Schlothauer, and Beate Röder "LEDs as excitation source for time resolved singlet oxygen luminescence detection in cell suspensions", Proc. SPIE 8568, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXII, 85680W (13 March 2013); https://doi.org/10.1117/12.2008185

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