20 March 2013 Freehand OCT with real-time lateral motion tracking
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Freehand optical coherence tomography (OCT) systems without mechanical scanners can offer greater freedom to access and image sites of interest. However, the scanning velocity during freehand scan is irregular; therefore pseudo B-scan images obtained by stacking sequentially acquired A-scans have a non-uniform spatial sampling rate in the lateral dimension. In this study, we developed a speckle decorrelation method to estimate lateral displacement between sequentially acquired A-scans and used the information extracted from speckle analysis to correct the time-varying lateral scanning speed. We applied this method to a handheld OCT probe and performed calibration experiments to validate our model. Furthermore we demonstrated distortion-free, freehand OCT imaging of various samples including human tissue, in vivo.
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Xuan Liu, Xuan Liu, Yong Huang, Yong Huang, Peter Gehlbach, Peter Gehlbach, Jin U. Kang, Jin U. Kang, } "Freehand OCT with real-time lateral motion tracking", Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 85711P (20 March 2013); doi: 10.1117/12.2006973; https://doi.org/10.1117/12.2006973


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