20 March 2013 Characterization of ovarian tissue using polarization-sensitive optical coherence tomography
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Abstract
We characterized ovarian tissue by using polarization-sensitive optical coherence tomography (PS-OCT). Phase retardation changing rate along with optical scattering coefficient and phase retardation were extracted from 33 ex vivo human ovaries from 18 patients. By using phase retardation changing rate as a classifier, we could achieve 71% sensitivity and 100% specificity. Combining those three parameters together, we could achieve 100% sensitivity and 100% specificity. These initial results showed that the quantitative analysis of PS-OCT could be a useful tool to characterize normal and malignant ovarian tissue.
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Tianheng Wang, Tianheng Wang, Yi Yang, Yi Yang, Xiaohong Wang, Xiaohong Wang, Melinda Sanders, Melinda Sanders, Molly Brewer, Molly Brewer, Quing Zhu, Quing Zhu, } "Characterization of ovarian tissue using polarization-sensitive optical coherence tomography", Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 857124 (20 March 2013); doi: 10.1117/12.2001515; https://doi.org/10.1117/12.2001515
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