20 March 2013 Imaging of electro-kinetic responses of tissues with optical coherence tomography
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Abstract
We have measured changes in optical coherence signals during the application of an external electric field to tissue samples. We employed the swept-source OCT engine with a broadband light source of 140-nm spectral bandwidth centered at 1300 nm. Switching the polarity of the electric field induced significant reversible changes in the phase of the OCT signal. Since the phase signal was corrupted by phase noise, it required a formidable signal processing to obtain the images of electrically induced phase changes.
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V. Demidov, V. Toronov, Y. Xu, B. Vuong, C. Sun, V. X. D. Yang, A. Vitkin, "Imaging of electro-kinetic responses of tissues with optical coherence tomography", Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 85712Q (20 March 2013); doi: 10.1117/12.2005910; https://doi.org/10.1117/12.2005910
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