22 March 2013 Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation
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Abstract
The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (StO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 – 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.
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Andrey V. Dunaev, Andrey V. Dunaev, Victor V. Sidorov, Victor V. Sidorov, Neil A. Stewart, Neil A. Stewart, Sergei G. Sokolovski, Sergei G. Sokolovski, Edik U. Rafailov, Edik U. Rafailov, } "Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation", Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857205 (22 March 2013); doi: 10.1117/12.2001797; https://doi.org/10.1117/12.2001797
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