22 March 2013 Portable wide-field hand-held NIR scanner
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Abstract
Near-infrared (NIR) optical imaging modality is one of the widely used medical imaging techniques for breast cancer imaging, functional brain mapping, and many other applications. However, conventional NIR imaging systems are bulky and expensive, thereby limiting their accelerated clinical translation. Herein a new compact (6 × 7 × 12 cm3), cost-effective, and wide-field NIR scanner has been developed towards contact as well as no-contact based real-time imaging in both reflectance and transmission mode. The scanner mainly consists of an NIR source light (between 700- 900 nm), an NIR sensitive CCD camera, and a custom-developed image acquisition and processing software to image an area of 12 cm2. Phantom experiments have been conducted to estimate the feasibility of diffuse optical imaging by using Indian-Ink as absorption-based contrast agents. As a result, the developed NIR system measured the light intensity change in absorption-contrasted target up to 4 cm depth under transillumination mode. Preliminary in-vivo studies demonstrated the feasibility of real-time monitoring of blood flow changes. Currently, extensive in-vivo studies are carried out using the ultra-portable NIR scanner in order to assess the potential of the imager towards breast imaging..
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Young-Jin Jung, Young-Jin Jung, Manuela Roman, Manuela Roman, Jennifer Carrasquilla, Jennifer Carrasquilla, Sarah J. Erickson, Sarah J. Erickson, Anuradha Godavarty, Anuradha Godavarty, } "Portable wide-field hand-held NIR scanner", Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 85720A (22 March 2013); doi: 10.1117/12.2002704; https://doi.org/10.1117/12.2002704
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