20 March 2013 Potential for using mid-infrared light for non-invasive, early-detection of skin cancers in vivo
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Abstract
The remarkable progress made towards mid-IR spectral in vitro mapping of tissue and cancer detection is reviewed, with emphasis on diagnosis of skin cancer. The status quo of chalcogenide glass mid-IR fiberoptics and photonics for meeting opportunities for remote mid-IR sensing in general, and in in vivo cancer detection in particular, is assessed. Raman spectroscopy is a sister technique to mid-IR spectroscopy. The current success of Raman spectroscopy in medical diagnosis is appraised, with particular emphasis on Raman spectral imaging of tissue towards skin cancer diagnosis in vivo, based on a silica-glass fiberoptic sensor-head. The challenges to be met in chalcogenide glass science and technology towards facilitating analogous fiberoptic diagnostics based on mid-IR spectroscopy are addressed.
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Angela B. Seddon, "Potential for using mid-infrared light for non-invasive, early-detection of skin cancers in vivo", Proc. SPIE 8576, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIII, 85760V (20 March 2013); doi: 10.1117/12.2019374; https://doi.org/10.1117/12.2019374
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