Use of diffuse optical spectroscopy to monitor muscle and brain oxygenation dynamics during isometric and isokinetic exercise

Goutham Ganesan; Joshua Cotter; Warren Reuland; Robert V. Warren; Soroush M. Mirzaei Zarandi; Albert E. Cerussi; Bruce J. Tromberg; Pietro Galassetti

doi:10.1117/12.2007459

25 March 2013 Use of diffuse optical spectroscopy to monitor muscle and brain oxygenation dynamics during isometric and isokinetic exercise

Goutham Ganesan, Joshua Cotter, Warren Reuland, Robert V. Warren, Soroush M. Mirzaei Zarandi, Albert E. Cerussi, Bruce J. Tromberg, Pietro Galassetti

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Proceedings Volume 8578, Optical Tomography and Spectroscopy of Tissue X; 857803 (2013) https://doi.org/10.1117/12.2007459
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

The use of near-infrared time-resolved spectroscopy (TRS-20, Hamamatsu Corporation) in two resistance type exercise applications in human subjects is described. First, using isometric flexion of the biceps, we compared the magnitude and relevance of tissue hemoglobin concentration and oxygen saturation (stO2) changes when assuming constant scattering versus continuous measurement of reduced scattering coefficients at three wavelengths. It was found that the assumption of constant scattering resulted in significant errors in hemoglobin concentration assessment during sustained isometric contractions. Secondly, we tested the effect of blood flow restriction (BFR) on oxygenation in a muscle (vastus medialis oblique, VMO) and in the prefrontal cortex (PFC) of the brain. The BFR training technique resulted in considerably more fatigability in subjects, and correlated with reduced muscle stO2 between sets of exertion. Additionally, exercise with BFR resulted in greater PFC deoxygenation than a condition with equivalent work performance but no BFR. These experiments demonstrate novel applications for diffuse optical spectroscopy in strength testing and targeted muscle rehabilitation.

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Goutham Ganesan, Joshua Cotter, Warren Reuland, Robert V. Warren, Soroush M. Mirzaei Zarandi, Albert E. Cerussi, Bruce J. Tromberg, and Pietro Galassetti "Use of diffuse optical spectroscopy to monitor muscle and brain oxygenation dynamics during isometric and isokinetic exercise", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 857803 (25 March 2013); https://doi.org/10.1117/12.2007459

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