Evaluation of Fourier transform coefficients for the diagnosis of rheumatoid arthritis from diffuse optical tomography images

Ludguier D. Montejo; Jingfei Jia; Hyun K. Kim; Andreas H. Hielscher

doi:10.1117/12.2004846

25 March 2013 Evaluation of Fourier transform coefficients for the diagnosis of rheumatoid arthritis from diffuse optical tomography images

Ludguier D. Montejo, Jingfei Jia, Hyun K. Kim, Andreas H. Hielscher

Author Affiliations +

Proceedings Volume 8578, Optical Tomography and Spectroscopy of Tissue X; 85781N (2013) https://doi.org/10.1117/12.2004846
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We apply the Fourier Transform to absorption and scattering coefficient images of proximal interphalangeal (PIP) joints and evaluate the performance of these coefficients as classifiers using receiver operator characteristic (ROC) curve analysis. We find 25 features that yield a Youden index over 0.7, 3 features that yield a Youden index over 0.8, and 1 feature that yields a Youden index over 0.9 (90.0% sensitivity and 100% specificity). In general, scattering coefficient images yield better one-dimensional classifiers compared to absorption coefficient images. Using features derived from scattering coefficient images we obtain an average Youden index of 0.58 ± 0.16, and an average Youden index of 0.45 ± 0.15 when using features from absorption coefficient images.

Citation Download Citation

Ludguier D. Montejo, Jingfei Jia, Hyun K. Kim, and Andreas H. Hielscher "Evaluation of Fourier transform coefficients for the diagnosis of rheumatoid arthritis from diffuse optical tomography images", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85781N (25 March 2013); https://doi.org/10.1117/12.2004846

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