Design of an optimized time-resolved diffuse optical tomography probe to achieve deep absorption contrast reconstruction in a cylindrical geometry

Anne Planat-Chrétien; Lionel Hervé; Michel Berger; Agathe Puszka; Jean-Marc Dinten

doi:10.1117/12.2003549

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25 March 2013 Design of an optimized time-resolved diffuse optical tomography probe to achieve deep absorption contrast reconstruction in a cylindrical geometry

Anne Planat-Chrétien, Lionel Hervé, Michel Berger, Agathe Puszka, Jean-Marc Dinten

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Proceedings Volume 8578, Optical Tomography and Spectroscopy of Tissue X; 857826 (2013) https://doi.org/10.1117/12.2003549
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We design a Time-Resolved (TR) instrumentation coupled with a reconstruction method based on Mellin-Laplace Transform (MLT) to accurately assess in depth absorption and diffusion maps of a cylindrical diffusive medium. To deal with experimental large TR dataset, MLT processing is handled without expressing the sensitivity matrix. Moreover an optimization of the TR probe geometry is performed to limit the number of measurements while keeping the sensitivity of the system. Simulations show how to optimize the probe geometry for specific inclusions depth given a background diffusing medium. These results lead to an experimental bench we use to perform experimental validations. This includes a femtosecond laser coupled with an HRI and a CCD camera.

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Anne Planat-Chrétien, Lionel Hervé, Michel Berger, Agathe Puszka, and Jean-Marc Dinten "Design of an optimized time-resolved diffuse optical tomography probe to achieve deep absorption contrast reconstruction in a cylindrical geometry ", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 857826 (25 March 2013); https://doi.org/10.1117/12.2003549

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