25 March 2013 Experimental investigation on region-based diffuse optical tomography
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Abstract
A region-based approach of image reconstruction using the finite element method is developed for diffuse optical tomography (DOT). The method is based on the framework of the pixel-based DOT methodology and on an assumption that different anatomical regions have their respective sets of the homogeneous optical properties distributions. With this hypothesis, the region-based DOT solution greatly improves the ill-posedness of the inverse problem by reducing the number of unknowns to be reconstructed. The experimental validation of the methodology is performed on a solid phantom employing a multi-channel DOT system of lock-in photon-counting mode, as well as compared with the traditional pixel-based reconstruction results, demonstrate that the proposed DOT methodology presents a promising tool of in vivo reconstructing background optical structures with the aid of anatomical a priori.
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Linhui Wu, Xi Yi, Wei Zhang, Jiao Li, Xin Wang, Limin Zhang, Huijuan Zhao, Feng Gao, "Experimental investigation on region-based diffuse optical tomography", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85782T (25 March 2013); doi: 10.1117/12.2001044; https://doi.org/10.1117/12.2001044
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