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25 March 2013 Experimental investigation on region-based diffuse optical tomography
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A region-based approach of image reconstruction using the finite element method is developed for diffuse optical tomography (DOT). The method is based on the framework of the pixel-based DOT methodology and on an assumption that different anatomical regions have their respective sets of the homogeneous optical properties distributions. With this hypothesis, the region-based DOT solution greatly improves the ill-posedness of the inverse problem by reducing the number of unknowns to be reconstructed. The experimental validation of the methodology is performed on a solid phantom employing a multi-channel DOT system of lock-in photon-counting mode, as well as compared with the traditional pixel-based reconstruction results, demonstrate that the proposed DOT methodology presents a promising tool of in vivo reconstructing background optical structures with the aid of anatomical a priori.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Linhui Wu, Xi Yi, Wei Zhang, Jiao Li, Xin Wang, Limin Zhang, Huijuan Zhao, and Feng Gao "Experimental investigation on region-based diffuse optical tomography", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85782T (25 March 2013);

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