4 March 2013 3D laser optoacoustic ultrasonic imaging system for preclinical research
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In this work, we introduce a novel three-dimensional imaging system for in vivo high-resolution anatomical and functional whole-body visualization of small animal models developed for preclinical or other type of biomedical research. The system (LOUIS-3DM) combines a multi-wavelength optoacoustic and ultrawide-band laser ultrasound tomographies to obtain coregistered maps of tissue optical absorption and acoustic properties, displayed within the skin outline of the studied animal. The most promising applications of the LOUIS-3DM include 3D angiography, cancer research, and longitudinal studies of biological distribution of optoacoustic contrast agents (carbon nanotubes, metal plasmonic nanoparticles, etc.).
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sergey A. Ermilov, Sergey A. Ermilov, André Conjusteau, André Conjusteau, Travis Hernandez, Travis Hernandez, Richard Su, Richard Su, Vyacheslav Nadvoretskiy, Vyacheslav Nadvoretskiy, Dmitri Tsyboulski, Dmitri Tsyboulski, Fatima Anis, Fatima Anis, Mark A. Anastasio, Mark A. Anastasio, Alexander A. Oraevsky, Alexander A. Oraevsky, "3D laser optoacoustic ultrasonic imaging system for preclinical research", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810N (4 March 2013); doi: 10.1117/12.2008811; https://doi.org/10.1117/12.2008811

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