4 March 2013 Fluence mapping inside the highly scattering medium using reflection mode acousto-optics
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Abstract
Optical excitation based imaging modalities, with aim to image structures deep inside the scattering medium, suffer from quantification problem. We propose a methodology to solve the problem of non-invasively mapping the fluence in optically heterogeneous medium without the need of prior knowledge of its optical properties. We present a theoretical model of our concept and provide proof of principle with Monte Carlo simulations. Simulation results show that it is possible to measure the local light fluence in highly scattering medium in absolute terms. Furthermore, we performed an experiment to validate the concept as a strategy to measure local fluence in relative manners. We used reflection mode acousto optics (AO) in our experiment, and showed that with this method we can measure local light fluence (in relative term) in highly scattering medium.
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Altaf Hussain, Altaf Hussain, Khalid Daoudi, Khalid Daoudi, Erwin Hondebrink, Erwin Hondebrink, Wiendelt Steenbergen , Wiendelt Steenbergen , } "Fluence mapping inside the highly scattering medium using reflection mode acousto-optics", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810U (4 March 2013); doi: 10.1117/12.2002383; https://doi.org/10.1117/12.2002383
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