4 March 2013 Optimization of the photoacoustic conversion of gold nanorods embedded in biopolymeric scaffolds
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Abstract
Gold nanorods exhibit intense optical absorbance in the near-infrared region of principal interest for applications in biomedical optics, which evokes their use to improve contrast in photoacoustic imaging and selective photothermolysis of cancer. However their limited photostability remains a drawback of practical concern. In particular, when GNRs are irradiated with nanosecond laser pulses in resonance with their plasmon oscillations, there may occur phenomena like reshaping into spherical particles, as well as fragmentation at higher optical fluences, which result into dramatic modifications of their optical absorption bands and substantial loss of photoacoustic conversion efficiency. In this contribution we present an experimental investigation of stability and photoacoustic conversion efficiency from gold nanorods embedded in biomimetic scaffolds.
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Lucia Cavigli, Lucia Cavigli, Marella De Angelis, Marella De Angelis, Fulvio Ratto, Fulvio Ratto, Paolo Matteini, Paolo Matteini, Francesca Rossi, Francesca Rossi, Sonia Centi, Sonia Centi, Roberto Pini, Roberto Pini, } "Optimization of the photoacoustic conversion of gold nanorods embedded in biopolymeric scaffolds", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810Z (4 March 2013); doi: 10.1117/12.2003173; https://doi.org/10.1117/12.2003173
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