28 February 2013 Color-matched esophagus phantom for fluorescent imaging
Author Affiliations +
We developed a stable, reproducible three-dimensional optical phantom for the evaluation of a wide-field endoscopic molecular imaging system. This phantom mimicked a human esophagus structure with flexibility to demonstrate body movements. At the same time, realistic visual appearance and diffuse spectral reflectance properties of the tissue were simulated by a color matching methodology. A photostable dye-in-polymer technology was applied to represent biomarker probed “hot-spot” locations. Furthermore, fluorescent target quantification of the phantom was demonstrated using a 1.2mm ultrathin scanning fiber endoscope with concurrent fluorescence-reflectance imaging.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chenying Yang, Vivian Hou, Leonard Y. Nelson, Eric J. Seibel, "Color-matched esophagus phantom for fluorescent imaging", Proc. SPIE 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V, 85830F (28 February 2013); doi: 10.1117/12.2000834; https://doi.org/10.1117/12.2000834

Back to Top