Color-matched esophagus phantom for fluorescent imaging

Chenying Yang; Vivian Hou; Leonard Y. Nelson; Eric J. Seibel

doi:10.1117/12.2000834

28 February 2013 Color-matched esophagus phantom for fluorescent imaging

Chenying Yang; Vivian Hou; Leonard Y. Nelson; Eric J. Seibel

Author Affiliations +

Proceedings Volume 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V; 85830F (2013) https://doi.org/10.1117/12.2000834
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

We developed a stable, reproducible three-dimensional optical phantom for the evaluation of a wide-field endoscopic molecular imaging system. This phantom mimicked a human esophagus structure with flexibility to demonstrate body movements. At the same time, realistic visual appearance and diffuse spectral reflectance properties of the tissue were simulated by a color matching methodology. A photostable dye-in-polymer technology was applied to represent biomarker probed “hot-spot” locations. Furthermore, fluorescent target quantification of the phantom was demonstrated using a 1.2mm ultrathin scanning fiber endoscope with concurrent fluorescence-reflectance imaging.

Citation Download Citation

Chenying Yang, Vivian Hou, Leonard Y. Nelson, Eric J. Seibel, "Color-matched esophagus phantom for fluorescent imaging", Proc. SPIE 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V, 85830F (28 February 2013); doi: 10.1117/12.2000834; https://doi.org/10.1117/12.2000834

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