22 February 2013 New developments in clinical CARS
Author Affiliations +
We combined two-photon fluorescence and coherent anti-Stokes Raman scattering (CARS) imaging in a clinical hybrid multiphoton tomograph for in vivo imaging of human skin. The clinically approved TPEF/CARS system provides simultaneous imaging of endogenous fluorophores and non-fluorescent lipids. The Stokes laser for the two-beam configuration of CARS is based on spectral broadening of femtosecond laser pulses in a photonic crystal fiber (PCF). We report on the highly flexible medical TPEF/CARS tomograph MPTflex®-CARS with an articulated arm and first in vivo measurements on human skin.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Martin Weinigel, Martin Weinigel, Hans Georg Breunig, Hans Georg Breunig, Marcel Kellner-Höfer, Marcel Kellner-Höfer, Rainer Bückle, Rainer Bückle, Maxim Darvin, Maxim Darvin, Juergen Lademann, Juergen Lademann, Karsten König, Karsten König, "New developments in clinical CARS", Proc. SPIE 8588, Multiphoton Microscopy in the Biomedical Sciences XIII, 85881E (22 February 2013); doi: 10.1117/12.2001855; https://doi.org/10.1117/12.2001855


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